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Arimidex is a powerful and highly selective non-steroidal aromatase inhibitor. In postmenopausal women, estradiol is mainly produced by converting androstenedione to estrone in peripheral tissues with the participation of the aromatase enzyme, then estrone is converted to estradiol. Lowering the level of estradiol in the blood has a therapeutic effect in women with breast cancer.
ARIMIDEX (Anastrozole) is used with other treatments, such as surgery or radiation, to treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods). This medication is also used in women, who have experienced menopause, as a first treatment of breast cancer that has spread within the breast or to other areas of the body. This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). ARIMIDEX (Anastrozole) is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow.

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