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Fortum Ceftazidime 500 mg for injection

$16.40

Fortum powder for Injection is an antibiotic medicine. It  given by injection (usually in hospital) to treat serious bacterial infections such as  septicaemia (blood poisoning), meningitis and lung infections in cysticfibrosis. It’s also used to treat complicated skin infections, abdominal infections, bone and joints infections, ear infections and complicated conditions, liver, kidney and urinary system, urinary tract infections.  It contains ceftazidime, which belongs to the antibiotic class of medicine.
Your doctor may prescribe ceftazidime injections if you have a low white blood cell count (neutropenia) and fever and your doctor suspects you have a bacterial infection.

Description

Buy Fortum Ceftazidime 500 mg for injection

Description of Fortum Ceftazidime 500 mg for injection:

Fortum powder for Injection is an antibiotic medicine. It  given by injection (usually in hospital) to treat serious bacterial infections such as  septicaemia (blood poisoning), meningitis and lung infections in cysticfibrosis. It’s also used to treat complicated skin infections, abdominal infections, bone and joints infections, ear infections and complicated conditions, liver, kidney and urinary system, urinary tract infections.  It contains ceftazidime, which belongs to the antibiotic class of medicine.
Your doctor may prescribe ceftazidime injections if you have a low white blood cell count (neutropenia) and fever and your doctor suspects you have a bacterial infection.
Men having surgery on their prostate gland (trans-urethral resection of the prostate or TURP) may be given this antibiotic to prevent urinary tract infections.
Fortum Injection contains a very useful drug named Ceftazidime. Ceftazidime is a 3rd generation, semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7 aminocephalosporic acid and closely related to penicillins in structure. That has the potential to be useful in treating gram-negative bacterial infections with respects to susceptible Enterobacteriaceae as well as Pseudomonas aeruginosa in dogs, cats, and reptiles. Ceftazidime is important to take the drug for the full time period as prescribed.If it disconnected during the therapy, it may result in ineffective treatment

Ingredients:

Active ingredient: ceftazidime;
1 vial contains ceftazidime (in the form of ceftazidime pentahydrate) 500 mg;
other components: sodium carbonate anhydrous.

Indication of Fortum Ceftazidime 500 mg for injection:

FORTUM is indicated for the treatment of patients with infections caused by susceptible strains of the designated organisms in the following diseases:

  • Lower Respiratory Tract Infections, including pneumonia, caused by Pseudomonas aeruginosa and other Pseudomonas spp.; Haemophilus influenzae, including ampicillin-resistant strains; Klebsiella spp.; Enterobacter spp.; Proteus mirabilis; Escherichia coli; Serratia spp.; Citrobacter spp.; Streptococcus pneumoniae; and Staphylococcus aureus (methicillin-susceptible strains).
  • Skin and Skin-Structure Infections caused by Pseudomonas aeruginosa; Klebsiella spp.; Escherichia coli; Proteus spp., including Proteus mirabilis and indole-positive Proteus; Enterobacter spp.; Serratia spp.; Staphylococcus aureus (methicillin-susceptible strains); and Streptococcus pyogenes (group A beta-hemolytic streptococci).
  • Urinary Tract Infections, both complicated and uncomplicated, caused by Pseudomonas aeruginosa; Enterobacter spp.; Proteus spp., including Proteus mirabilis and indolepositive Proteus; Klebsiella spp.; and Escherichia coli.
  • Bacterial Septicemia caused by Pseudomonas aeruginosa, Klebsiella spp., Haemophilus influenzae, Escherichia coli, Serratia spp., Streptococcus pneumoniae, and Staphylococcus aureus (methicillin-susceptible strains).
  • Bone and Joint Infections caused by Pseudomonas aeruginosa, Klebsiella spp., Enterobacter spp., and Staphylococcus aureus (methicillin-susceptible strains).
  • Gynecologic Infections, including endometritis, pelvic cellulitis, and other infections of the female genital tract caused by Escherichia coli.
  • Intra-abdominal Infections, including peritonitis caused by Escherichia coli, Klebsiella spp., and Staphylococcus aureus (methicillin-susceptible strains) and polymicrobial infections caused by aerobic and anaerobic organisms and Bacteroides spp. (many strains of Bacteroides fragilis are resistant).
  • Central Nervous System Infections, including meningitis, caused by Haemophilus influenzae and Neisseria meningitidis. Ceftazidime has also been used successfully in a limited number of cases of meningitis due to Pseudomonas aeruginosa and Streptococcus pneumoniae.
  • Ceftazidime may be used alone in cases of confirmed or suspected sepsis. Ceftazidime has been used successfully in clinical trials as empiric therapy in cases where various concomitant therapies with other antibacterial drugs have been used.
  • Ceftazidime may also be used concomitantly with other antibacterial drugs, such as aminoglycosides, vancomycin, and clindamycin; in severe and life-threatening infections; and in the immunocompromised patient. When such concomitant treatment is appropriate, prescribing information in the labeling for the other antibacterial drugs should be followed. The dose depends on the severity of the infection and the patient’s condition.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftazidime and other antibacterial drugs, Ceftazidime should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Contraindications of Fortum Ceftazidime 500 mg for injection:

  • Patients with known hypersensitivity to cephalosporin antibiotics.
  • On the other hand, Hypersensitivity to the medication pentahydrate or to any of the ingredients of the product

Side Effects of Fortum Ceftazidime 500 mg for injection:

  • Swelling, redness, or pain at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
  • Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
  • Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, unusual tiredness, shaking, muscle spasms, uncontrollable movements, mental/mood changes (such as confusion), seizures, signs of kidney problems (such as change in the amount of urine), signs of liver problems (such as nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine).
  • This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn’t stop, abdominal or stomach pain/cramping, blood/mucus in your stool.
  • Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because these products may make them worse.
  • Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
  • A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
  • This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions and Warnings of Fortum Ceftazidime 500 mg for injection:

  • Before using ceftazidime tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (such as penicillins, other cephalosporins); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, stomach/intestinal diseases (such as colitis).
  • Ceftazidime may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
  • There is limited information about the safety of this medicine during pregnancy. Your doctor will prescribe you this medicine only if considered essential after assessing the benefits over risks.
  • This medicine can be taken while breastfeeding if prescribed by the doctor.
  • Avoid driving if you feel dizzy after taking Fortum Powder For Injection.
  • Although there is no known interaction with alcohol along with this medicine, it is important to consult your physician if you have a habit of regular drinking.

Other General Warnings
Talk to your doctor if:

  • You have a history of allergy to penicillins or any medicines.
  • You develop any allergic reaction after taking this medicine.
  • You are suffering from diarrhoea due to this medicine.
  • You should let the doctor, or the laboratory person know that you are using this medicine while going for a lab test, as this medicine may interfere with certain lab tests.

Storage:

Before opening: Fortum Powder For Injection at 20º to 25°C. Protect from light.
After opening: Properly reconstituted solution of Ceftazidime are stable for 12 hours at room temperature or 3 days if refrigerated (5°C). Slight yellowing does not affect potency.

Shelf life:

3 year

Before using the drug, be sure to consult your doctor.

Application Features

As with other beta-lactam antibiotics, severe and sometimes fatal hypersensitivity reactions have been reported. In severe hypersensitivity reactions, treatment with ceftazidime should be stopped immediately and appropriate urgent measures taken.

Before starting treatment, the patient should be determined for a history of severe hypersensitivity reactions to ceftazidime, cephalosporin antibiotics, or other beta-lactam antibiotics. Use with caution in patients who have had mild hypersensitivity reactions to other beta-lactam antibiotics.

Ceftazidime has a limited spectrum of antibacterial activity. It is not an acceptable agent for the monotherapy of certain types of infections unless the causative agent is known to be susceptible to treatment or there is a strong possibility that the potential pathogen will be susceptible to treatment with ceftazidime. This is especially important when considering the treatment of patients with bacteremia, bacterial meningitis, skin and soft tissue infections, and bone and joint infections. In addition, ceftazidime is susceptible to hydrolysis by some extended-spectrum beta-lactamases. Therefore, when choosing ceftazidime for treatment, information on the spread of microorganisms producing extended-spectrum beta-lactamases should be taken into account.

Concomitant treatment with high doses of cephalosporins and nephrotoxic drugs such as aminoglycosides or potent diuretics (eg furosemide) may adversely affect renal function. Experience with the clinical use of ceftazidime has shown that this phenomenon is unlikely when the recommended dosage is observed. There is no evidence that ceftazidime has an adverse effect on renal function at usual therapeutic doses.

Ceftazidime is excreted by the kidneys, so the dose should be reduced according to the degree of kidney damage. Cases of neurological complications have been reported when the dose has not been reduced accordingly.

As with other broad-spectrum antibiotics, prolonged treatment with Fortum may result in overgrowth of non-susceptible organisms (eg, Candida, Enterococci); in this case, it may be necessary to stop treatment or take other necessary measures. It is very important to constantly monitor the patient’s condition.

Cases of pseudomembranous colitis have been reported with the use of antibiotics, which can range in severity from mild to life-threatening. Therefore, it is important to consider establishing this diagnosis in patients who develop diarrhea during or after antibiotic use. In case of prolonged and significant diarrhea or the patient develops abdominal cramps, treatment should be stopped immediately, further examination of the patient should be carried out and, if necessary, specific treatment for Clostridium difficile should be prescribed. Do not prescribe drugs that slow down intestinal motility.

As with other broad-spectrum cephalosporins and penicillins, some strains of Enterobacter spp. and Serratia spp. may become resistant to ceftazidime treatment. In such cases, sensitivity studies should be carried out periodically.

Fortum contains sodium in its composition (1 vial of 500 mg of ceftazidime contains 26 mg (1.15 mmol) of sodium, a vial of 1 g of ceftazidime contains 52 mg (2.3 mmol) of sodium, a vial of 2 g of ceftazidime contains 104 mg (4.6 mmol) of sodium.
Use during pregnancy or lactation

Data on the treatment of pregnant women with ceftazidime are limited. Animal studies do not indicate direct or indirect harmful effects on pregnancy, embryonic or postnatal development. The drug should be prescribed to pregnant women only when the benefit of its use outweighs the possible risk.

Ceftazidime is excreted into breast milk in small amounts, but no effects on breastfeeding are expected at therapeutic doses. Ceftazidime can be used during breastfeeding.

The ability to influence the reaction rate when driving vehicles or operating other mechanisms

Relevant studies have not been conducted. But certain adverse reactions (such as dizziness) may occur, which may affect the ability to drive vehicles or other mechanisms.

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Additional information

Weight 175 g
Country/Region of Manufacture

Italy

Manufacturer

GlaxoSmithKline (GSK)

Forms of release

Powder

Volume/Weight

1 g

Packing

Cardboard Box, Glass bottle

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