Mucous cell infiltrates characterizing rhinosinusitis and asthma are similar (such as eosinophilic leukocytes, mastocytes, macrophagocytes and T-lymphocytes).
In addition, pro-inflammatory carriers are present in both the nasal and bronchial mucous membrane (for example, histamine, leukotrienes, interleicitis, granulocytic and monocyte colony factors (GMKSF), activation of expression and secretion of normal T-cells and adhesion molecules) . Such as:
The effect of segmental pulmonary allergen (for example, the direct administration of allergen into the lungs through bronchoscopy) leads to a noticeable inflammatory reaction of patients with allergies and without asthma.
The effect of nasal allergen can lead to bronchial inflammation in patients with allergic rhinitis, but without clinical signs of asthma.
Eosinophilic leukocytes are found in more quantities in patients with asthma and allergic rhinitis than in patients only asthma.
In patients with asthma with or without the history of rhinitis, with the help of a biopsy, the growing level of eosinophilic leukocytes is determined.
In individuals with allergic rhinitis, but without asthma, responding to a bronchial pipe with a reaction to metacoline, an increase in eosinophilic leukocytes in the nasal mucosa is found.