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Β The drug contains bupivacaine, a long-acting local anesthetic of the amide type with anesthetic and analgesic effects. At high doses, surgical anesthesia is achieved, while at lower doses, sensory blockade (analgesia) is achieved, accompanied by a less pronounced motor blockade. The onset and duration of the local analgesic effect depend on the dose and site of administration of the drug. Bupivacaine reversibly blocks the conduction of impulses by nerve fibers by inhibiting the transport of sodium ions across the cell membranes of nerve fibers. Similar effects can be observed on the excitatory membranes of the brain and myocardium. The most significant property of bupivacaine is the long duration of its effect.
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