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Nimesil contains nimesulide as an active ingredient – NSAIDs with predominant inhibitory activity against the COX-2 enzyme. Nimesulide has a complex mechanism of action, including the reduction of free radical formation and other components of neutrophil activation, which further explains its anti-inflammatory activity.
Nimesulide has powerful analgesic, anti-inflammatory and antipyretic properties with a relatively low risk of side effects from the gastrointestinal tract, as evidenced by the results of numerous clinical studies. In addition, when administered orally, it is rapidly absorbed, which makes it possible to effectively stop acute pain.
Nimesulide exhibits therapeutic efficacy in a diverse range of diseases that have an inflammatory component in the pathogenesis and are manifested by pain syndrome. So, it significantly alleviates the severity of the symptoms of rheumatoid arthritis and osteoarthritis, reducing the intensity of pain both at rest and during movement, increasing the range of motion and reducing the severity and duration of morning stiffness, as well as pain on palpation of the affected joints.

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