The active substance of the drug is bupivacaine, a long-acting local anesthetic of the amide type with anesthetic and analgesic effects. At high doses, surgical anesthesia is achieved, while low doses lead to sensory blockade (analgesia), which is accompanied by less pronounced motor blockade. The onset and duration of the local analgesic effect depends on the dose and site of administration of the drug. The most significant property of bupivacaine is the long duration of its effect. The difference between the duration of effect of bupivacaine with and without epinephrine is relatively small. Bupivacaine is particularly suitable for long-term epidural blockade. Lower concentrations may be suitable for long-term pain relief, such as during childbirth or in the postoperative period.
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